Proceedings: Urinary cytology in the assessment of progress after renal transplantation.

MARGARET BISSON, P. BISSON, D. SPRATT, AND SYLVIA DAVIES (Renal Unit, Whipton Hospital and Area Department of Pathology, Exeter) Cytological examination of the urine has provided immediate indication of early rejection after renal transplantation. The appearance of activated lymphocytes and immunoblasts in the urinary deposit correlates well with other parameters of rejection, such as reduced renal function and increased peripheral blood lymphocyte count. Other abnormalities, including tubular necrosis and infection, can be identified and differentiated from those of rejection. Results can be reported within an hour after receipt of a fresh sample of urine.